Stuart Holden has been ruled out for six months after damaging knee ligaments in the defeat by Manchester United last time out, while Mark Davies is a major doubt as he continues to battle an ankle injury.
That means Tamir Cohen could make his first Premier League start of the season, with England Under-21 international Fabrice Muamba also in contention.
Zat Knight (knee) is back in training but not yet ready for a return, while Sean Davis (knee) and Sam Ricketts (Achilles) are both long-term absentees.
Source: PA
Source: PA