Knight is expected to miss the next four to six weeks after damaging ligaments in his right knee in Sunday's 2-0 win over Everton while Sturridge, who has scored three goals in three games since arriving on loan from Chelsea, is cup-tied.
David Wheater will come in for Knight while Trotters boss Owen Coyle plans to make up to five other changes as he gives an opportunity to some of his fringe players.
Source: PA
Source: PA