The Mirror says Melchiot has been axed from the side and could be on the move in the transfer window as Bruce looks to shake up his struggling club.
The former Chelsea defender is on a big wage at St Andrews but has not figured for the past month.
Bolton chief Sam Allardyce is now on red alert and is ready to move for the Dutchman with Nicky Hunt sidelined with injury.
Meanwhile, Bolton could also be lining up a bid for Sheffield United defender Phil Jagielka.
The News of the World says Trotters boss Sam Allardyce is ready to make the England U21 star his record signing with a bid of £4 million in January.
Jagielka is also a target for Aston Villa and Birmingham City.