The former West Ham midfielder was stretchered off with just seven minutes played, with sought-after centre-back Gary Cahill giving Owen Coyle's men the lead just before the break with a lethal strike.
It got worse for Neil Warnock's side on 67 minutes when Danny Gabbidon, another player signed on a free transfer from West Ham this summer, turned the ball past his own goalkeeper to double the lead.
Croatian forward Ivan Klasnic added a third three minutes later with a deflected shot and it was soon four when Fabrice Muamba ran onto a Klasnic pass to finish well.
QPR's frustration boiled over as Clint Hill was sent off in added time for an incident with Martin Petrov.
Spectacular strike: Gary Cahill (centre top) rocketed Bolton ahead just before half-time
MATCH FACTSQPR: Kenny, Hill, Hall, Gabbidon, Derry, Taarabt, Dyer, Faurlin, Campbell, Bothroyd, Smith.
Substitutes: Murphy, Orr, Connolly, Buzsaky, Ephraim, Agyemang, Helguson.Bolton: Jaaskelainen, Steinsson, Robinson, Cahill, Knight, Muamba, Eagles, Petrov, Reo-Coker, Kevin Davies, Klasnic.
Substitutes: Bogdan, Alonso, Wheater, Gardner, Mark Davies, Pratley, Blake.
How they stand: Premier League table
More to follow...
Not again: Kieron Dyer is stretchered off after breaking his metatarsal in his left foot
.
Nightmare: Danny Gabbidon turns the ball past his own goalkeeper to double the lead
.
Lucky: Ivan Klasnic's deflected shot makes it 3-0
.
Great start: Paul Robinson (left) celebrates Bolton's cracking opening day victory
.
?QPR v Bolton: How the action unfolded at Loftus RoadWatch all the Premier League goals every week on our brilliant video playerAll the latest QPR news, features and opinionAll the latest Bolton news, features and opinion
Source: Daily Mail
Source: Daily Mail