Michael Bridges and Bedi Buval both had chances early on to score for Bolton whilst at the other end David Jones went close for United on a couple of occasions.
Five minutes before half time the Red Devils took the lead when striker Sylvain Ebanks-Blake fired a curling shot beyond Andy Oakes in the Wanderers goal but in all fairness the first half had been pretty evenly balanced.
The Trotters almost snatched an immediate response shortly after the interval when substitute James Sinclair was unlucky to see his attempt blocked by United's teenage goalkeeper Tom Heaton.
Former England youth player Chris Eagles doubled United's advantage with twenty minutes to go when he fired a wind assisted shot into the roof of the Bolton net and this practically spelt the end of the game for the home side who had seen their United counterparts step up a gear in the second period.
Ricardo Vaz-Te and Bridges once again could have reduced the defacit but a goal by Italian striker Guiseppe Rossi wrapped things up for the Reds Devils with just a few minutes to go.
BOLTON RESERVES: Andy Oakes, Ricky Shakes, Jason Talbot, Florent Laville, Charlie Comyn-Platt, Blessing Kaku, Joey O'Brien, Reda Kribib (Ricardo Vaz-Te), Dale Whitehead, Michael Bridges, Bedi Buval (James Sinclair)
SUBS NOT USED: Chris Howarth, Rhys Powell, Bradley Hill
UNITED RESERVES: Tom Heaton, Phil Picken, Paul Tierney, Mark Howard, Paul McShane, David Fox, Chris Eagles (David Poole), David Jones, Sylvain Ebanks-Blake, Guiseppe Rossi, Bojan Djordic
SUBS NOT USED: Ben Collett, Crockett, Richard Jones, Floribert N'Galula